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Published on: March 16, 2018
Acute otitis media in children: a retrospective analysis of physician prescribing patterns
Caroline Quach1, Jean-Paul Collet, Jacques LeLorier
1Pharmacoepidemiology Unit, Research Institute, CHUM, Campus Hôtel-Dieu, University of Montreal, Montreal (QC), Canada.
Insights
Pediatric acute otitis media (AOM) antibiotic prescribing patterns show low adherence to guidelines. Continuing medical education is crucial to improve appropriate antibiotic use in children with AOM.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pharmacology
Background:
- Acute otitis media (AOM) is a common childhood infection and a leading reason for antibiotic prescriptions.
- Understanding AOM treatment patterns is vital for optimizing antibiotic stewardship in pediatric populations.
Purpose of the Study:
- To analyze prescribing patterns and assess the appropriateness of antibiotic therapy for acute otitis media in children.
- To evaluate physician adherence to established AOM treatment guidelines.
Main Methods:
- A historical cohort study of children aged 6 years or younger with a first AOM episode was conducted using administrative healthcare databases.
- Prescription conformity was assessed against consensus guidelines, with data analyzed using descriptive statistics and logistic regression.
Main Results:
- Over 60,000 children experienced their first AOM episode, with amoxicillin being the most frequently prescribed antibiotic.
- Only 42% of physicians adhered to AOM treatment guidelines; ENT specialists were less likely to follow guidelines compared to GPs and pediatricians.
Conclusions:
- Significant gaps exist in physician adherence to AOM antibiotic guidelines.
- Targeted continuing medical education is recommended to enhance appropriate antibiotic prescribing for AOM in children.
Background:
Acute otitis media (AOM) is one of the most common infectious diseases of childhood and the most frequent indication for antibiotic use in children. Aim To better understand the prescribing patterns and appropriateness of AOM therapy.
Methods:
We investigated a historical cohort of children aged < or = 6 years who had a first AOM episode between June 1999 and June 2002, using the Régie de l'assurance maladie du Quebec (RAMQ) administrative databases. Conformity of prescription was based on the consensus guidelines on AOM treatment from the Drug-resistant Streptococcus pneumoniae Therapeutic Working Group. These recommendations suggested amoxicillin as the first-line drug, and amoxicillin-clavulanic acid or cefuroxime for children who had received antibiotics in the previous month. Data were analysed using descriptive statistics, chi(2) test and logistic regression.
Results:
During the study period, 60 513 children < or = 6 years of age experienced their first AOM episode with a mean age of 2.6 years. They were seen by 4708 physicians [87% general practitioners (GPs), 9% paediatricians, and 3% ENT specialists]. Amoxicillin was the antibiotic that was prescribed the most (43%), followed by cefprozil and azithromycin. Overall, 42% of physicians adhered to antibiotic guideline recommendations. Compared with GPs, paediatricians were almost as likely to prescribe in conformity with the consensus guidelines, whereas ENT specialists were 50% less likely to prescribe an antibiotic recommended by the guidelines.
Conclusion:
Continuing medical education is necessary to ensure appropriate adherence to antibiotic guidelines.
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