Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acute phenobarbital intoxication.

M C Lindberg1, A Cunningham, N H Lindberg

  • 1Department of Internal Medicine, University of Alabama School of Medicine, Tuscaloosa 35487-0378.

Southern Medical Journal
|August 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Implementation of Positive Advanced Recovery Connections in Primary and Secondary Mental Health Care-A Registered Advanced Nurse Practitioner-Led Initiative.

Journal of advanced nursing·2024
Same author

Gut microbiota analysis and faecal transplantation to improve surgical outcomes.

The British journal of surgery·2023
Same author

Chemical characterisation of the vapour emitted by an e-cigarette using a ceramic wick-based technology.

Scientific reports·2022
Same author

Conservation in a Region of Political Instability: Bwindi Impenetrable Forest, Uganda.

Conservation biology : the journal of the Society for Conservation Biology·2022
Same author

Quality of internet information to aid patient decision making in locally advanced and recurrent rectal cancer.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2022
Same author

The Chemical Complexity of e-Cigarette Aerosols Compared With the Smoke From a Tobacco Burning Cigarette.

Frontiers in chemistry·2021
Same journal

The Five Essential Concepts of Developmental Medicine: A Medical Paradigm for People with Developmental Disabilities.

Southern medical journal·2026
Same journal

α-Gal Syndrome in the South: Why We Need Treatment Trials, Not Just Tick Prevention.

Southern medical journal·2026
Same journal

Association between Main Pancreatic Duct Size, Comorbidities, and Fistula Formation after Whipple Procedure for Pancreatic Cancer.

Southern medical journal·2026
Same journal

Impact of Temperature Variation on Patients with Acute Severe Asthma.

Southern medical journal·2026
Same journal

Assessing the Accuracy and Reliability of ChatGPT-4 to Answer Clinical EHR Messages in Sports Medicine.

Southern medical journal·2026
Same journal

Diagnostic Utility and Clinical Implications of Inpatient Fecal Occult Blood Testing.

Southern medical journal·2026
See all related articles

Phenobarbital overdose is a medical emergency. Management includes supportive care, activated charcoal, and alkaline diuresis, with dialysis for severe cases.

Area of Science:

  • Pharmacology
  • Toxicology
  • Emergency Medicine

Background:

  • Phenobarbital, a long-acting barbiturate, is prescribed for seizure disorders.
  • It possesses a high abuse potential and historical association with suicide attempts.
  • While benzodiazepines are now more common in overdoses, barbiturate intoxications remain a critical concern.

Purpose of the Study:

  • To outline the critical management strategies for phenobarbital overdose.
  • To highlight the ongoing relevance of barbiturate toxicity in emergency medicine.

Main Methods:

  • Review of established medical protocols for barbiturate overdose.
  • Emphasis on supportive care, gastrointestinal decontamination, and enhanced elimination techniques.

Related Experiment Videos

Main Results:

  • Effective management hinges on prompt cardiac and respiratory support.
  • Activated charcoal and cathartics aid in drug elimination.
  • Alkaline diuresis enhances renal excretion of phenobarbital.

Conclusions:

  • Phenobarbital overdose requires immediate medical intervention and comprehensive management.
  • Advanced interventions like hemodialysis and hemoperfusion are vital for critically ill patients.
  • Understanding phenobarbital toxicity is crucial for emergency physicians.