Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional genomics and proteomics: application in neurosciences.

K E Wilson1, M M Ryan, J E Prime

  • 1MRC Building, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, UK.

Journal of Neurology, Neurosurgery, and Psychiatry
|March 18, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification and evaluation of barriers and facilitators to formal help-seeking for premenstrual symptoms in the UK: a mixed methods approach.

Frontiers in global women's health·2026
Same author

Improving care experiences for premenstrual symptoms and disorders in the United Kingdom (UK): a mixed-methods approach.

BMC health services research·2025
Same author

Cystic ovarian disease in dairy cattle: Diagnostic accuracy when using B-mode and color Doppler ultrasound.

Journal of dairy science·2023
Same author

Reliability and validity of the FSHD-composite outcome measure in childhood facioscapulohumeral dystrophy.

Neuromuscular disorders : NMD·2021
Same author

Development of clinical practice guidelines for allied health and nursing assessment and management of Duchenne muscular dystrophy.

Disability and rehabilitation·2021
Same author

Is Reluctance to Share Alzheimer's Disease Biomarker Status with a Study Partner a Barrier to Preclinical Trial Recruitment?

The journal of prevention of Alzheimer's disease·2020
Same journal

Global epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Diagnostic accuracy of a two-cut-off approach using the FAQ/MMSE ratio and FAQ for clinical preselection of patients for anti-amyloid therapy.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Cancer risk and mortality in patients with multiple sclerosis in Finland: a retrospective population-based cohort study.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Characteristics and outcomes in electric scooter-related traumatic brain injuries in Helsinki.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Chronological ageing and ovarian reserve in MS: insights from anti-Müllerian hormone and disability progression.

Journal of neurology, neurosurgery, and psychiatry·2026
See all related articles

Large-scale gene and protein expression analysis is crucial for understanding complex biological systems and diseases. This review explores current high-throughput methods and their limitations for comprehensive biological insights.

Area of Science:

  • Genomics
  • Proteomics
  • Systems Biology

Background:

  • Complete genome sequencing enables a systematic understanding of biological systems.
  • Traditional analysis methods are insufficient for the complexity of modern biological research.
  • High-throughput analysis is essential for capturing the full biological picture.

Purpose of the Study:

  • To review current large-scale gene and protein expression analysis methods.
  • To discuss the limitations of existing high-throughput techniques.
  • To guide the selection of appropriate methods for maximizing data in biological research.

Main Methods:

  • Review of large-scale gene expression analysis techniques.
  • Review of large-scale protein expression analysis techniques.

Related Experiment Videos

  • Comparative analysis of method capabilities and limitations.

    • Main Results:

    • Identification of various high-throughput methods for gene and protein analysis.
    • Discussion of the strengths and weaknesses of each method.
    • Emphasis on the importance of choosing the right method for specific research questions.

    Conclusions:

    • Large-scale analysis is vital for understanding health and disease.
    • The choice of method significantly impacts the completeness of biological data.
    • Further development and critical evaluation of high-throughput methods are needed.