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Bioptic techniques in flexible endoscopy. An experimental study in the pig.
J L Hedenbro1, M Ekelund, R Willen
1Department of Surgery, Lund University, Sweden.
Surgical Endoscopy
|May 1, 1992
Summary
The Crosta technique, involving diathermy snare excision of mucosa, best obtains submucosal gastric tissue. Other biopsy methods showed less depth, though biopsy size was comparable. Spiked forceps offered a slight advantage for gastric biopsies.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
- Surgical Pathology
Background:
- Biopsies of submucosal gastric lesions often have low success rates.
- Accurate tissue acquisition is crucial for diagnosing gastric pathologies.
Purpose of the Study:
- To compare the efficacy of three common biopsy techniques in obtaining submucosal gastric tissue.
- To evaluate the impact of biopsy forceps type (spiked vs. non-spiked) on tissue acquisition.
Main Methods:
- An experimental study was conducted using a pig model.
- Three biopsy techniques were tested: Crosta (diathermy snare excision), Seifert (hole-in-hole), and Asaki (ethanol injection).
- Biopsies were taken using both spiked and non-spiked forceps.
Main Results:
- The Crosta technique yielded the best results for obtaining submucosal tissue.
- The Seifert and Asaki techniques were less effective in achieving biopsy depth.
- Biopsy size was not significantly different between the Seifert and Asaki techniques.
- Biopsy forceps with a central spike demonstrated a slight superiority over non-spiked forceps.
Conclusions:
- The Crosta technique is the most effective method for acquiring submucosal gastric biopsies.
- Biopsy forceps design, specifically the presence of a spike, can offer a marginal improvement in tissue yield.
- Further research may optimize endoscopic biopsy strategies for challenging submucosal gastric lesions.