Developmental function of very-low-birth-weight infants and full-term infants in early childhood

Pei-Shan Chen1, Suh-Fang Jeng, Kuo-Inn Tsou

  • 1School and Graduate Institute of Physical Therapy and Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

Insights

Very-low-birth-weight (VLBW) infants show higher risks for functional impairments in areas like motor skills and communication compared to full-term infants. Early screening and follow-up are crucial for VLBW infants facing developmental challenges.

Area of Science:

  • Pediatric developmental assessment
  • Neonatal outcomes research
  • Childhood functional status evaluation

Background:

  • Surviving very-low-birth-weight (VLBW) infants face increased risks for neurodevelopmental impairments and educational difficulties.
  • Limited research exists on the functional status of VLBW survivors in key developmental domains.

Purpose of the Study:

  • To assess and compare the functional status of VLBW infants and full-term infants in early childhood.
  • To identify risk factors associated with functional morbidity in VLBW infants.

Main Methods:

  • Prospective follow-up study including 238 VLBW infants and 91 full-term infants.
  • Functional status assessed using the Chinese Child Development Inventory (CCDI).
  • Neurodevelopment evaluated with Bayley Scales of Infant Development (BSID-II) at 3 years corrected age.

Main Results:

  • VLBW infants scored lower on all CCDI measures compared to full-term infants.
  • Significantly higher rates of functional limitations (gross motor, fine motor, language, self-help, social) in VLBW infants.
  • Risk factors for functional morbidity included prematurity (<30 weeks GA), intraventricular hemorrhage, chronic lung disease, retinopathy of prematurity, male gender, and lower maternal education.

Conclusions:

  • VLBW infants exhibit a greater risk of functional morbidity in early childhood.
  • CCDI screening can identify VLBW infants needing comprehensive developmental assessment and ongoing follow-up.
Abstract

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