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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Developmental function of very-low-birth-weight infants and full-term infants in early childhood
Pei-Shan Chen1, Suh-Fang Jeng, Kuo-Inn Tsou
1School and Graduate Institute of Physical Therapy and Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Insights
Very-low-birth-weight (VLBW) infants show higher risks for functional impairments in areas like motor skills and communication compared to full-term infants. Early screening and follow-up are crucial for VLBW infants facing developmental challenges.
Area of Science:
- Pediatric developmental assessment
- Neonatal outcomes research
- Childhood functional status evaluation
Background:
- Surviving very-low-birth-weight (VLBW) infants face increased risks for neurodevelopmental impairments and educational difficulties.
- Limited research exists on the functional status of VLBW survivors in key developmental domains.
Purpose of the Study:
- To assess and compare the functional status of VLBW infants and full-term infants in early childhood.
- To identify risk factors associated with functional morbidity in VLBW infants.
Main Methods:
- Prospective follow-up study including 238 VLBW infants and 91 full-term infants.
- Functional status assessed using the Chinese Child Development Inventory (CCDI).
- Neurodevelopment evaluated with Bayley Scales of Infant Development (BSID-II) at 3 years corrected age.
Main Results:
- VLBW infants scored lower on all CCDI measures compared to full-term infants.
- Significantly higher rates of functional limitations (gross motor, fine motor, language, self-help, social) in VLBW infants.
- Risk factors for functional morbidity included prematurity (<30 weeks GA), intraventricular hemorrhage, chronic lung disease, retinopathy of prematurity, male gender, and lower maternal education.
Conclusions:
- VLBW infants exhibit a greater risk of functional morbidity in early childhood.
- CCDI screening can identify VLBW infants needing comprehensive developmental assessment and ongoing follow-up.
Background And Purpose:
Despite general recognition that surviving very-low-birth-weight (VLBW) infants are at risk for neurodevelopmental impairments and educational achievement difficulties, there has been relatively little study on their functional status in areas such as locomotion, communication, cognition, self-care, and interpersonal relationships. This study assessed the functional status of VLBW infants and full-term infants in early childhood, and sought to identify risk factors for functional morbidity.
Methods:
A total of 238 VLBW infants and 91 full-term infants were included in this prospective follow-up study. The functional status of the infants was assessed using the Chinese Child Development Inventory (CCDI) and neurodevelopment was evaluated using the Bayley Scales of Infant Development, second version (BSID-II) at 3 years of corrected age. Perinatal and sociodemographic data were collected through review of medical records.
Results:
The VLBW infants had lower scores on all the CCDI measures compared with the full-term infants. Functional limitation (defined as more than 2 standard deviations below the means of the full-term infants) occurred more frequently in the VLBW infants than in the full-term infants: gross motor, 23% vs 3%; fine motor, 12% vs 1%; expressive language, 21% vs 2%; comprehension-conceptual, 23% vs 4%; situation comprehension, 17% vs 4%; self-help, 17% vs 1%; and personal-social, 19% vs 3% (all p < 0.01). Significant risk factors associated with functional morbidity included gestational age < 30 weeks, grade III-IV intraventricular hemorrhage, chronic lung disease, stage III-IV retinopathy of prematurity, male gender, and maternal education below high school.
Conclusion:
VLBW infants have a higher risk of functional morbidity than their full-term counterparts in early childhood. Infants with functional limitations on CCDI screening might require comprehensive developmental assessment and continued follow-up.
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