Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Histoplasmosis masquerading as tuberculosis: a case report.

Nagesh S Babu1, Pankaj Malhotra, B D Radotra

  • 1Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh.

Indian Journal of Pathology & Microbiology
|March 19, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of cellular casein kinase II in the function of the phosphoprotein (P) subunit of RNA polymerase of vesicular stomatitis virus.

The Journal of biological chemistry·1995
Same author

Case of the month: a painful red eye.

The British journal of radiology·1995
Same author

Double reading of magnetic resonance imaging films.

The National medical journal of India·1995
Same author

Local excision of rectal tumours.

The British journal of surgery·1995
Same author

Human parainfluenza virus type 3 phosphoprotein: identification of serine 333 as the major site for PKC zeta phosphorylation.

Virology·1995
Same author

An audit of fatal acute pancreatitis.

Postgraduate medical journal·1995

Histoplasmosis is a rare fungal infection in India. A patient presenting with leucopenia and hepatosplenomegaly, initially treated for tuberculosis, was diagnosed with progressive disseminated histoplasmosis post-mortem.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Pathology

Background:

  • Histoplasmosis is an opportunistic fungal infection caused by Histoplasma capsulatum.
  • It is infrequently reported in India, making its clinical presentation less recognized.
  • Disseminated tuberculosis is a common differential diagnosis in endemic regions.

Observation:

  • A patient presented with persistent leucopenia (low white blood cell count) and hepatosplenomegaly (enlarged liver and spleen).
  • The initial clinical suspicion and treatment were directed towards disseminated tuberculosis.
  • Autopsy revealed findings consistent with progressive disseminated histoplasmosis.

Findings:

  • The autopsy confirmed progressive disseminated histoplasmosis as the underlying diagnosis.

Related Experiment Videos

  • The case highlights a diagnostic challenge where histoplasmosis mimicked tuberculosis.
  • Persistent leucopenia and hepatosplenomegaly were key clinical indicators.

    • Implications:

    • This case underscores the importance of considering histoplasmosis in the differential diagnosis of similar presentations in India.
    • Improved diagnostic awareness can lead to earlier and more appropriate treatment of histoplasmosis.
    • Further epidemiological studies are needed to understand the true prevalence of histoplasmosis in India.