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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Endogenous beta-carbolines as clonidine-displacing substances

E S J Robinson1, N J Anderson, J Crosby

  • 1Psychopharmacology Unit, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK.

Annals of the New York Academy of Sciences
|March 19, 2004
PubMed
Summary

Harmane and related beta-carbolines are endogenous ligands for imidazoline-binding sites (IBS) in humans. Evidence suggests these compounds play a role in mammalian physiology, acting on specific binding sites.

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