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Related Experiment Videos

[Microflora of the voice prostheses].

V O Ol'shanskiĭ1, E N Novozhilova, V V Dvornichenko

  • 1Moskovskiĭ nauchno-issledovatel'skiĭ institut im. P. A. Gertsena, gorodskaia onkologicheskaia bol'nitsa #62, Moskva; Irkutskiĭ oblastnoĭ onkodispanser.

Vestnik Otorinolaringologii
|March 19, 2004
PubMed
Summary

Voice prostheses can become contaminated with fungi and bacteria, leading to leakage and reduced function. Antifungal therapy can double the lifespan of these essential medical devices.

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Area of Science:

  • Otolaryngology
  • Medical Microbiology

Background:

  • Voice prostheses, such as Provox and Blom-Singer, are crucial for alaryngeal speech rehabilitation after laryngectomy.
  • These devices are implanted in a tracheoesophageal puncture (TEP) to restore voice production.
  • Long-term device integrity and function are essential for patient quality of life.

Observation:

  • A study examined 27 patients using voice prostheses for 6 months to 2 years.
  • Contamination of the esophageal flange and protective valve with fungi and pathogenic bacteria was observed upon removal.
  • Deformation and reduced motility of the valve led to leakage into the airways.

Findings:

  • Bacteriological analysis identified Candida albicans, Candida krusei, and Candida glabralis in 11 patients.
  • Fungal contamination compromised the prosthesis's watertight seal and motility.

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  • Antifungal treatments (Nystatin, Flucostat, Fluconazole, Amphotericin) were administered.

    • Implications:

    • Prophylactic antifungal therapy can significantly extend the functional use of voice prostheses, potentially doubling their lifespan.
    • Addressing microbial contamination is critical for maintaining voice prosthesis function and preventing complications.
    • Further research into preventative strategies against microbial biofilm formation on voice prostheses is warranted.