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Updated: Aug 25, 2026

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source
Published on: February 7, 2013
[Hemoglobin concentration in children from birth to one year of age]
Sophia Cornbluth Szarfarc1, Sonia Buongermino de Souza, Rosemeire Aparecida Victória Furumoto
1Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brasil.
Insights
Infant anemia is prevalent in Brazil, affecting over 50% of 6-12 month olds. Low birth weight increases risk, while breastfeeding is protective in early months, but complementary foods show no impact on hemoglobin levels.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Hemoglobin (Hb) concentration is a critical indicator of infant health.
- Understanding factors influencing Hb levels is vital for early childhood development programs.
Purpose of the Study:
- To investigate the evolution of hemoglobin concentration in infants.
- To identify the influence of birth weight, growth rate, and food intake on infant Hb levels.
Main Methods:
- Cross-sectional study design involving infants under 1 year of age.
- Data collected through public health services across Brazil's five geographic regions.
- Hemoglobin concentration estimated using theoretical equations and analyzed in relation to growth parameters and diet.
Main Results:
- Anemia prevalence was 51.7% in infants aged 6 to 12 months.
- Low birth weight infants exhibited a higher prevalence of reduced Hb levels.
- Breastfeeding was associated with adequate Hb in early months, but complementary foods did not significantly influence Hb concentration.
- Growth rate was not found to be a relevant factor for hemoglobin concentration.
Conclusions:
- Endogenous iron supports normal Hb levels in the first three months of life.
- High anemia prevalence underscores the need for targeted public health interventions.
- Nutritional strategies should focus on early life iron status, considering birth weight and breastfeeding practices.
Abstract:
This study aimed to describe the evolution of hemoglobin concentration considering the following factors: birth weight, growth rate, and food intake. The cross-sectional study focused on infants (<1 year of age) whose growth and development were monitored by public health services in cities located in the five geographic regions of Brazil. Some 51.7% of the children aged 6 to 12 months presented anemia. Estimation of [Hb] concentration by a theoretical equation suggested that endogenous iron is able to maintain normal Hb levels in the first three months of life. Prevalence of reduced Hb was higher in low birth weight infants. Growth rate, verified by the difference between present weight and birth weight in Z scores, was not the relevant factor for hemoglobin concentration. The relevance of breastfeeding was evident in the initial months of life. However, complementary foods did not influence infant Hb concentration. The high prevalence of low Hb levels calls attention to the need for programs to control anemia.
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