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[Renal dysplasia: clinico-pathologic review].
A S Cunha1, J F de Sousa, C Garcia
1Laboratório de Anatomia Patológica, Escola Superior de Medicina Dentária de Lisboa, Hospital de D. Estefânia.
Acta Medica Portuguesa
|May 1, 1992
Summary
This study reviews 27 cases of kidney dysplasia, finding it most common in young boys, often presenting with urinary tract infections or abdominal masses. Early diagnosis is crucial for managing this congenital condition.
Area of Science:
- Pediatric Nephrology
- Uropathology
- Congenital Kidney Disorders
Context:
- Review of 63 nephrectomies identified 27 cases of kidney dysplasia.
- Analysis included unilateral totally dysplastic kidneys and polar/segmental dysplasia.
- Clinicopathological correlation was performed on all cases.
Purpose:
- To conduct a clinicopathological study of kidney dysplasia.
- To review theories on the pathogenesis of kidney dysplasia.
- To emphasize the importance of diagnosing kidney dysplasia.
Summary:
- Unilateral total dysplasia predominantly affected males under two years, with urinary tract infections as the most common presentation.
- Segmental dysplasia cases, diagnosed from 27 weeks gestation to 8 years, often involved duplex kidneys and ureterocele.
- Histological findings included multicystic and solid dysplasia, with one case showing metaplastic cartilage; inflammatory changes were more pronounced in segmental dysplasia.
Impact:
- Highlights common clinical presentations and associated anomalies in pediatric kidney dysplasia.
- Provides insights into histological variations within dysplastic kidney disease.
- Underscores the clinical significance of timely diagnosis for congenital kidney anomalies.