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Recurrent abdominal pain in children: the utility of upper endoscopy and histopathology
N Ukarapol1, N Lertprasertsuk, L Wongsawasdi
1Department of Paediatrics, Chiang Mai University, Chiang Mai 50200, Thailand. nukarapo@mail.med.cmu.ac.th
Insights
Upper endoscopy with biopsy is a valuable tool for diagnosing recurrent abdominal pain in children. Helicobacter pylori gastritis was the most common organic cause identified, with antral nodularity as a key endoscopic finding.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Endoscopy
Background:
- Recurrent abdominal pain is a common pediatric complaint.
- Identifying organic causes is crucial for effective management.
Purpose of the Study:
- To evaluate the diagnostic utility of upper gastrointestinal endoscopy with biopsy.
- To identify common organic causes of clinically significant recurrent abdominal pain in children.
Main Methods:
- Prospective study of 38 children with severe recurrent upper abdominal pain.
- Inclusion criteria: >= 3 episodes impairing activity, requiring medical attention.
- All patients underwent upper gastrointestinal endoscopy with biopsy after initial assessment.
Main Results:
- Organic causes identified in 44.7% of cases.
- Helicobacter pylori gastritis was the most frequent diagnosis (28.9%).
- Antral nodularity showed significant association with H. pylori infection (sensitivity 63.4%, specificity 85.2%).
Conclusions:
- Upper endoscopy with biopsy is effective in diagnosing pediatric recurrent abdominal pain.
- Helicobacter pylori infection is a prevalent cause in this population.
- Specific therapies led to improvement in all patients.
Introduction:
To study the utility of upper gastrointestinal endoscopy with biopsy in the evaluation of children with clinically-significant recurrent abdominal pain.
Methods:
Over a three-month period, children with three or more episodes of upper abdominal pain that was severe enough to impair their normal activity and required medical attention were included in the study. After complete history, physical examination and basic investigations, upper gastrointestinal endoscopy with biopsy was performed in all patients.
Results:
Thirty-eight children were enrolled. Their average age was 10.5 years and 21 were female. Organic causes were identified in 44.7 percent of the cases, with Helicobacter pylori gastritis being the most common diagnosis (28.9 percent). No specific dyspeptic symptom was significantly associated with either organic cause of recurrent abdominal pain or Helicobacter pylori infection. Antral nodularity was the only endoscopic finding significantly associated with Helicobacter pylori infection (sensitivity 63.4 percent, specificity 85.2 percent). All patients improved after specific therapy was instituted.
Conclusion:
The organic causes of recurrent abdominal pain in children have been increasingly identified in our hospital, a tertiary care centre in Northern Thailand. One of the most common causes found in this study was Helicobacter pylori infection. Upper endoscopy was very helpful in identifying the underlying pathology.
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