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[Oxygenator thrombosis without heparin resistance]

J-J Lehot1, B Waz, L Dendeleu

  • 1Service d'anesthésie-réanimation, hôpital Louis-Pradel, BP Lyon-Montchat, 69394 Lyon cedex 03, France. jean.jacques.lehot@chu-lyon.fr

Annales Francaises D'Anesthesie Et De Reanimation
|March 20, 2004
PubMed

A 55-year-old male with a history of positive HIV serology and Polycytemia vera underwent coronary artery bypass graft surgery with normothermic extracorporeal circulation. Following heparin administration the activated clotting time (ACT) was 633 seconds (Hemocron) with kaolin). Lower than expected arterial and venous oxygen partial pressures together with high pressure (350 mmHg) in the arterial line upstream of the oxygenator were observed. Because of these signs the oxygenator was changed during the procedure. The outcome was uneventful. Electronic microscopic examination of the oxygenator membrane and thermic exchanger revealed fibrin and platelet deposits.

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