Related Experiment Video
Updated: Aug 25, 2026

02:30
Endoscopic Approach for Colloid Cyst Resection
Published on: May 23, 2025
Wolf-Hirschhorn syndrome with posterior intraorbital coloboma cyst: an unusual case
Filiz Tutunculer1, Betul Acunas, Tufan Hicdonmez
1Istanbul University Istanbul Faculty of Medicine, Department of Pediatrics, Istanbul Turkey. ftutunculer@yahoo.com
Brain & Development
|March 20, 2004
Abstract:
Wolf-Hirschhorn syndrome (WHS) is associated with partial deletion of short arm of chromosome 4, and characterized by severe growth retardation. Other characteristic features are microcephaly, intellectual handicap, Greek helmet facies and closure deficits such as cleft lip or cleft palate, coloboma of the eye, and cardiac septal defect. We herein present a new case of WHS with bilateral iris colobomata and a left intraorbital large coloboma cyst causing exophthalmos.
