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Cloning and sequencing of the porcine lactoferrin cDNA
L J Alexander1, W B Levine, C T Teng
1Division of Surgical Oncology, University of Illinois, Chicago.
Animal Genetics
|January 1, 1992
Abstract:
cDNA clones encoding the entire porcine lactoferrin protein were isolated and sequenced. The porcine lactoferrin cDNA sequence presented here is 2259bp in length and encodes a leader peptide of 19 amino acids and a mature protein of 684 amino acids. Comparisons with other lactoferrins indicate a single glycosylation site. The iron- and anion-binding sites, and the cysteine residues involved in disulphide bonds, are conserved between the lactoferrin proteins.