Related Experiment Video
Updated: Aug 25, 2026

A Set of In Situ Informed Simulated Medium Formats for Culturing Environmentally Acquired Anaerobic Microorganisms
Published on: January 12, 2024
Reactions in unusual media
Daniel Clarke1, Mohammed A Ali, Anthony A Clifford
1Department of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.
Abstract:
This review provides an introduction to three of the most well-developed solvent replacement strategies currently under investigation for synthetic chemistry: Ionic liquids, fluorous phase techniques, and supercritical carbon dioxide. They are all fascinating reaction media, and have considerable potential for use in pharmaceutical synthesis. However, this has to be balanced with problems and limitations of the new methods. This review aims to provide an overall account of recent advances in the use of unusual media for synthetic chemistry, with an emphasis on highlighting potential benefits, but also limitations, of each of the methods described.
Related Concept Videos
Microbial Growth Media
Fast Reactions
Designing Growth Media for Bioreactors
Other Unique Bacteria

