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Published on: June 10, 2025
Epidemiological and pharmacological profile of congestive heart failure at Turkish academic hospitals
Ali Ergin1, Namik Kemal Eryol, Sükrü Unal
1Department of Cardiology, Erciyes University Medical School, Kayseri, Turkey. ergina@erciyes.edu.tr
Insights
This study reviewed congestive heart failure (CHF) treatment in Turkish hospitals. Key findings indicate suboptimal use of ACE inhibitors and beta-blockers, despite improvements in patient functional class.
Area of Science:
- Cardiology
- Internal Medicine
- Public Health
Background:
- Congestive heart failure (CHF) poses a significant health burden globally.
- Effective management of CHF is crucial for improving patient outcomes and reducing healthcare costs.
- Understanding current treatment practices is essential for identifying areas for improvement.
Purpose of the Study:
- To evaluate the current treatment status of congestive heart failure (CHF) in academic hospitals across Turkey.
- To identify patterns in medication use, patient demographics, and CHF etiology within this cohort.
- To assess the effectiveness of in-hospital management in improving patient functional status.
Main Methods:
- A retrospective analysis of 661 consecutive patients diagnosed with CHF from 16 academic hospitals in Turkey.
- Data collection included pre-admission, in-hospital, and discharge treatments, along with patient demographics, CHF causes, and laboratory findings.
- Patient functional classification using the New York Heart Association (NYHA) system was assessed at admission and discharge.
Main Results:
- The study included 661 patients with a mean age of 61 years. Ischemic CHF was more prevalent in men, while hypertension and rheumatic CHF were more common in women.
- A significant improvement in functional class was observed, with 90% of patients initially in NYHA class III-IV, reducing to 2% in class IV at discharge.
- While high rates of diuretic (95%) and aspirin (86%) use were noted, the utilization of angiotensin-converting enzyme (ACE) inhibitors (77%) and particularly beta-blockers (3%) was suboptimal.
Conclusions:
- Current treatment protocols for congestive heart failure (CHF) in Turkish academic hospitals show room for improvement, particularly regarding the uptake of evidence-based therapies.
- The utilization of ACE inhibitors, a cornerstone of CHF management, remains below optimal levels.
- Increased implementation and prescription of beta-blockers are strongly recommended to enhance CHF patient care and outcomes.
Objective:
We aimed to investigate the status of the treatment of congestive heart failure (CHF) in academic hospitals in Turkey.
Methods:
Overall 661 successive patients from 16 academic hospitals were included in this retrospective study. In addition to treatments given to the patients before admission to hospital, during their hospital stay, and at hospital discharge, data regarding their functional classifications, causes of CHF, and laboratory findings were also recorded.
Results:
In our study the mean age of patients was 61+/-12 years and the mean hospital stay 10+/-6 days. Ischemic CHF was observed more frequently in men (72% vs. 46%, p<0.001), while hypertension and rheumatic CHF were more frequent in women (27% vs. 19%, p<0.001 and 24% vs. 9%, p<0.001 respectively). While 90% of patients were in NYHA III-IV class at admission to hospital, only 2% of patients were in class IV at hospital discharge. The proportion of smokers was greater in men than in women (68% vs. 12%). Atrial fibrillation was present in 35% of patients. During hospitalization, angiotensin converting enzyme (ACE) inhibitors were used by 77%, diuretics by 95%, digitalis by 76%, nitrate by 85%, beta-blockers by 3%, aspirin by 86%, anticoagulants by 44%, Ca antagonist by 10%, positive inotropic agents by 42%; and antiarrhythmic agents by 15% of patients.
Conclusion:
The use of ACE inhibitors, the major milestone of CHF treatment, is not on an adequate level yet. The use of beta-blockers should also be encouraged.
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