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Updated: Aug 12, 2026

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
Published on: September 1, 2016
A psychophysical test of the vibration theory of olfaction
Andreas Keller1, Leslie B Vosshall
1Laboratory of Neurogenetics and Behavior, The Rockefeller University, 1230 York Avenue, Box 63, New York New York, 10021, USA. kellera@mail.rockefeller.edu
Abstract:
At present, no satisfactory theory exists to explain how a given molecule results in the perception of a particular smell. One theory is that olfactory sensory neurons detect intramolecular vibrations of the odorous molecule. We used psychophysical methods in humans to test this vibration theory of olfaction and found no evidence to support it.
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