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Interval between births and risk of congenital cytomegalovirus infection

Karen B Fowler1, Sergio Stagno, Robert F Pass

  • 1Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham,USA. kfowler@uab.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|March 23, 2004
PubMed

To examine the effect of the interval between maternal cytomegalovirus (CMV) infection and conception on the risk of congenital CMV infection, the congenital CMV infection rate was evaluated relative to the intervals between deliveries in young women. Among mothers who seroconverted between deliveries, the rate of congenital CMV infection among their offspring was highest when the delivery interval was < or =24 months. However, the risk of transmission remained elevated for women with delivery intervals of 25-48 months and for those with delivery intervals >48 months apart.

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