Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Eyeblink conditioning in the developing rat.

M E Stanton1, J H Freeman, R W Skelton

  • 1U.S. Environmental Protection Agency, Research Triangle Park, North Carolina.

Behavioral Neuroscience
|August 11, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydroallantois in a mare associated with schistosomus and unilateral ovarian agenesis in the fetus.

Journal of equine veterinary science·2024
Same author

WHO next-generation partograph: revolutionary steps towards individualised labour care.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Epidemiology and management of bacterial leaf spot on watermelon caused by Pseudomonas syringae.

Plant disease·2019
Same author

Mr. Key's Case of Ulceration of the Cartilages of the Larynx.

The Medical quarterly review·2018
Same author

Nano-Magnesium Oxide: A Novel Bactericide Against Copper-Tolerant Xanthomonas perforans Causing Tomato Bacterial Spot.

Phytopathology·2018
Same author

Human papillomavirus genotypes in Pacific Islander cervical cancer patients.

Gynecologic oncology reports·2018
Same journal

Hippocampal communication with the anterior olfactory nucleus is necessary for context-dependent odor memory.

Behavioral neuroscience·2026
Same journal

Biological sex and normative cognitive aging across spatial learning, flexibility, and working memory in Fischer 344 rats.

Behavioral neuroscience·2026
Same journal

Defensive antinociception and antipredatory responses in prey threatened by distinct odoriferous cues from Felis silvestris catus.

Behavioral neuroscience·2026
Same journal

Taste exposure during different developmental phases impacts aversion learning in adult rats.

Behavioral neuroscience·2026
Same journal

Structural neuroanatomy of semantic retrograde memory in older adults.

Behavioral neuroscience·2026
Same journal

Oxytocin prevents cocaine-induced high-affect 50-kHz vocalizations in female rats.

Behavioral neuroscience·2026
See all related articles

Young rats learned eyeblink conditioning (EBC), with older pups showing faster learning. This study explores EBC development in rat pups to understand learning and neural maturation.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Behavioral Science

Background:

  • Eyeblink conditioning (EBC) is a well-established model for studying associative learning.
  • Previous research utilized EBC in adult rats, but its ontogeny in developing animals is less understood.
  • Understanding learning processes in early development is crucial for comprehending neural maturation.

Purpose of the Study:

  • To investigate the feasibility and developmental trajectory of eyeblink conditioning (EBC) in Long-Evans rat pups.
  • To examine age-related differences in learning speed and associative capabilities during early development.
  • To explore factors influencing EBC acquisition, such as response ability, sensory sensitivity, and motivational state.

Main Methods:

  • Long-Evans rat pups at 17-18 days and 24 days of age were subjected to delay eyeblink conditioning.

Related Experiment Videos

  • The conditioning procedure involved pairing an auditory conditioned stimulus (tone) with a periocular-shock unconditioned stimulus (US).
  • Multiple sessions with controlled inter-trial intervals and trial numbers were administered.

    • Main Results:

    • Eyeblink conditioning was observed in rat pups at both tested ages (17-18 and 24 days).
    • Older pups (24 days) demonstrated significantly faster learning rates compared to younger pups (17-18 days).
    • Subsequent experiments confirmed the associative nature of the learning and ruled out age-related differences in motor response or US sensitivity.

    Conclusions:

    • Eyeblink conditioning is a viable paradigm for studying associative learning in developing rats.
    • Significant age-related improvements in learning speed occur during early postnatal development.
    • This preparation offers a valuable model for investigating the interplay between neural development and the ontogeny of learning.