What do we know about patients dying in the emergency department?
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Updated: Aug 25, 2026

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
Published on: August 5, 2020
Peter Vanbrabant1, Erwin Dhondt, Marc Sabbe
1Emergency Department, University Hospital Leuven, Herestraat 49, B-3000 Leuven, Belgium. peter.vanbrabant@uz.kuleuven.ac.be
Insights
Autopsies are crucial for determining the cause of death in emergency department (ED) patients when clinical diagnosis is unclear. Many deaths in the ED have discrepancies between presumed and actual causes, highlighting the need for autopsy.
Area of Science:
- Medical Science
- Pathology
- Emergency Medicine
Background:
- Determining the cause of death in emergency department (ED) patients is critical for medical understanding and public health.
- Accurate death certification is essential for accurate mortality statistics and quality improvement.
Purpose of the Study:
- To assess the accuracy of death certification for patients expiring in the ED.
- To evaluate the role of autopsy in clarifying the cause of death for these patients.
Main Methods:
- A retrospective chart review was conducted for all patients who died in an academic tertiary hospital's ED over one year.
- Clinical data, autopsy reports, and pathological investigations were analyzed to determine the cause of death.
Main Results:
- Of 196 deaths, 141 had a clinically determined cause. Autopsy in 29 cases with unknown antemortem diagnosis revealed the cause in all but one.
- Major causes of death included cardiac (19.4%), cerebral (16.8%), and trauma (15.3%).
- A significant discrepancy (15.3%) was found between the presumed and actual cause of death, with no class I autopsy findings indicating missed critical diagnoses.
Conclusions:
- Autopsy is vital for accurately establishing the cause of death in emergency department fatalities.
- The concordance between antemortem presumed cause of death and the actual cause is poor, underscoring the limitations of clinical diagnosis alone.
Objective:
To determine our knowledge in terms of cause of death and quality of death certification about patients who die in the emergency department. To establish the role of autopsy in this matter.
Methods:
Retrospective chart review of all patients dying in an academic emergency department (ED) of a tertiary hospital over a period of 1 year.
Results:
One hundred and ninety-six patients died in the ED in 1998. In 141/196 patients the cause of death could be determined on clinical grounds. In 53/196 patients, the antemortem clinical diagnosis was unknown. Twenty-nine out of 53 patients underwent autopsy. In all but one patient autopsy revealed the cause of death. After retrospective analysis of all patient data (notes, biology, radiology and pathological investigation), the major causes of death were cardiac (19.4%), cerebral (non-traumatic) (16.8%), trauma (15.3%) and unknown (13.3%). In the patient group with sudden cardiac arrest of unclear origin, the postmortem cause of death was identified as cardiac (51.7%), non-traumatic bleeding (10.3%), infectious (10.3%) and pulmonary embolism (3.4%). In the group of patients with a clinically clear cause of death, who underwent autopsy, 14 class II findings according to the Goldman's classification of autopsy diagnoses (i.e. major diagnosis whose detection would not have altered therapy nor outcome) were found in 16 patients. No class I findings (i.e. major diagnosis whose detection would have altered therapy or outcome) were noted. Altogether, major discrepancies between the antemortem presumed cause of death according to the notes and the real cause of death was found in 15.3%.
Conclusions:
Autopsy remains a very important tool to establish the cause of death in patients dying in ED. The concordance between the antemortem presumed cause of death recorded in the patient notes and the real cause (all patient data) is poor.
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