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Updated: Aug 25, 2026

Multi-step Preparation Technique to Recover Multiple Metabolite Compound Classes for In-depth and Informative Metabolomic Analysis
Published on: July 11, 2014
Strategies for dealing with metabolite elucidation in drug discovery and development
Alaa-Eldin F Nassar1, Rasmy E Talaat
1Department of Drug Metabolism, Wyeth Research, 500 Arcola Road, Collegeville, PA 19426, USA. NassarAL@aol.com
Abstract:
Structural information on metabolites can be a considerable asset for enhancing and streamlining the process of developing new drug candidates. Modern approaches that generate and use metabolite structural information can accelerate the drug discovery and development process by eliminating potentially harmful candidates earlier in the process and improving the safety of new drugs. This review examines the relative merits of current and potential strategies for dealing with metabolite characterization.
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