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Updated: Aug 25, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
Quantitative assessment of parenchymal and ventricular readjustment to intracranial pressure relief
Christoph Preul1, Marc Tittgemeyer, Dirk Lindner
1Max-Planck-Institute of Human Cognitive and Brain Science, Stephenstrasse 1a, 04103 Leipzig, Germany.
Abstract:
A 26-year-old patient underwent endoscopic third ventriculostomy for the treatment of obstructive hydrocephalus. 3D volume data sets were obtained at 3 T before surgery and three times after surgery. Off-line analysis of individual imaging data (initial linear registration, intensity adjustment, and final nonlinear registration of pre- to postoperative MR images) yielded 3D displacement fields representing the postoperative structural brain change. In principle, such an analysis technique can be used in any clinical follow-up for which careful observation of tissue readjustment is of particular importance.
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