Severity of ovarian hyperstimulation syndrome: its relation to number of conceptuses

To assess the possibility that number of days of hospital stay increases with an increasing number of conceptuses in patients with ovarian hyperstimulation syndrome (OHSS).

We reviewed 100 OHSS patients who were treated with a conservative therapeutic approach; 15 patients conceived but experienced spontaneous abortion by 8 weeks' gestation (SA group), 24 patients conceived a single fetus (singleton group), 16 patients conceived 2 fetuses (n = 14) or 3 fetuses (n = 2) (multiple group), and 45 patients did not conceive (NC group). The number of days of hospital stay, number of days of albumin supplementation, and hospital days when patients exhibited a urine volume of > or = 1200 mL/day and a hematocrit of > 40% were compared among the four groups.

The number (SD) of days of hospital stay was 23.6 (9.0) days for the multiple group, 16.5 (7.7) days for the singleton group, 13.9 (7.6) days for the SA group, and 11.6 (4.8) days for the NC group. The orders of the other three variables were the same as that of the number of days of hospital stay, in that a larger number of days was observed with an increasing number of conceptuses.

Pregnant women sustained OHSS for a longer time with an increasing number of conceived fetuses.