Related Experiment Video
Updated: Aug 25, 2026

Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis
Published on: May 12, 2019
Pathobiology of mucositis
1Harvard School of Dental Medicine, Boston, MA, USA.
Objective:
To describe the pathogenesis of mucositis, summarize the techniques used to study the condition, and describe the current five-phase model that defines mucositis pathogenesis.
Data Source:
Published research articles, ongoing laboratory and clinical studies, and clinical experience.
Conclusion:
Defining the biological mechanisms associated with mucosal injury is critical for effective intervention. Research performed over the past few years has shown that the pathobiology of mucositis is complex, and involves all of the cells and tissues of the mucosa.
Implications For Nursing Practice:
An understanding of this evolving pathobiologic model of mucositis will enable nurses to more effectively assess and manage mucositis.
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