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[Intestinal dysmotility-pseudo-obstruction].

J M Gil Vernet1, J M Casasa, J Boix Ochoa

  • 1Departamento de Cirugía, Hospital Materno-Infantil Vall d'Hebrón, Barcelona.

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica
|April 1, 1992
PubMed
Summary
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Diagnosis of chronic intestinal pseudo-obstruction relies on histologic criteria. Cisapride effectively treated neuropathic forms, aiding in distinguishing localized from diffuse disease presentations.

Area of Science:

  • Gastroenterology
  • Pathology

Context:

  • Chronic intestinal pseudo-obstruction (CIPO) is a complex motility disorder affecting intestinal regulation.
  • It can stem from muscular, neurogenic, or hormonal origins, excluding mechanical obstructions.

Purpose:

  • To investigate diagnostic methods and treatment efficacy for CIPO.
  • To differentiate between localized and diffuse forms of the condition.

Summary:

  • Eleven patients with CIPO were studied, including nine with hyperganglionisms and two with visceral myopathies (Berdon's syndrome).
  • Diagnosis was confirmed histologically using various staining techniques.
  • Intestinal motility was assessed via manometry, differentiating localized and diffuse disease patterns.
  • Medical management included total parenteral nutrition and cisapride, with surgical intervention for diffuse cases.

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Impact:

  • Histologic examination is crucial for CIPO diagnosis.
  • Complementary tests aid in distinguishing localized from diffuse disease.
  • Cisapride demonstrated efficacy in treating neuropathic CIPO.