Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Milking of microalgae.

M Amin Hejazi1, Rene H Wijffels

  • 1Food and Bioprocess Engineering Group, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands.

Trends in Biotechnology
|March 25, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermal acclimation and nitrogen deprivation drive distinct transcriptomic reprogramming toward a shared lipid phenotype in the polar marine microalga Chlamydomonas malina RCC2488.

Journal of biotechnology·2026
Same author

Co-Culture of Mammalian Cells and Photosynthetic Microorganisms for Oxygen Supply in Engineered Tissues.

Cell proliferation·2026
Same author

Extraction mechanisms of proteins from Palmaria palmata.

Food chemistry·2026
Same author

Intensification of Palmaria palmata protein biorefinery using multifrequency ultrasonication and enzymes.

Ultrasonics sonochemistry·2026
Same author

Real-time holographic monitoring of insect cell morphology during baculovirus coinfection for adeno-associated virus vector production using machine learning-based classification models.

New biotechnology·2026
Same author

Impact of multiplicity of infection and baculovirus co-infection ratio on recombinant adeno-associated virus vector production in insect cells.

Frontiers in bioengineering and biotechnology·2025
Same journal

Bacterial spores as a modular platform for the production of amyloids for materials.

Trends in biotechnology·2026
Same journal

The oriGen case and Mexico's regulatory blind spots in genomic biobanking.

Trends in biotechnology·2026
Same journal

A caspase-3-activated protein expression system for apoptosis visualization and apoptosis-pyroptosis conversion to boost antitumor activity.

Trends in biotechnology·2026
Same journal

Over 4 months of ethylene production using solid-state photosynthetic cell factories.

Trends in biotechnology·2026
Same journal

Closing the nitrogen loop in groundwater with biohybrid technologies.

Trends in biotechnology·2026
Same journal

Engineering environmental bacteria for whole-cell PET hydrolysis and assimilation.

Trends in biotechnology·2026
See all related articles

Continuous microalgal cultures can overcome low productivity for high-value compounds. Harvesting beta-carotene from Dunaliella salina suggests potential for milking other secondary metabolites from microalgae.

Area of Science:

  • Biotechnology
  • Algal Biotechnology
  • Metabolic Engineering

Background:

  • Low productivity of algal cultures is a major barrier to commercializing high-value compounds.
  • Continuous cultivation with cell reuse offers a potential solution to enhance productivity.
  • A novel method for harvesting beta-carotene from Dunaliella salina in a two-phase bioreactor has been developed.

Purpose of the Study:

  • To investigate the feasibility of applying the "milking" process to mass produce secondary metabolites from microalgae.
  • To understand the mechanism of the milking process and its connection to product formation pathways.
  • To determine if various microalgal species can be utilized for milking different products.

Main Methods:

  • Utilizing a two-phase bioreactor system for microalgal cultivation.

Related Experiment Videos

  • Harvesting beta-carotene from Dunaliella salina without cell destruction.
  • Analyzing the relationship between the milking process and secondary metabolite production pathways.
  • Main Results:

    • Successful "milking" of beta-carotene from Dunaliella salina demonstrates the potential of the technique.
    • The study provides insights into the mechanism of the milking process in microalgae.
    • The findings suggest that the milking process may be applicable to other microalgal species and products.

    Conclusions:

    • The "milking" process is a promising strategy to improve the economic viability of microalgal high-value compound production.
    • Further research is needed to explore the application of this technique across diverse microalgal species and secondary metabolites.
    • Understanding the underlying mechanisms is crucial for optimizing and expanding the use of microalgal milking technology.