Related Experiment Videos
Research for control: the onchocerciasis experience.
1Intervention Development and Implementation Research, UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, WHO, Geneva, Switzerland. remmej@who.int
Tropical Medicine & International Health : TM & IH
|March 26, 2004
Summary
Research significantly advanced onchocerciasis control in Africa over 20 years. Key contributions include epidemiological modeling, ivermectin trials, and community-directed strategies for sustained drug delivery.
Area of Science:
- Public Health
- Tropical Medicine
- Epidemiology
Background:
- Onchocerciasis control programs in Africa have achieved notable success.
- Research has been instrumental in guiding and evaluating these control efforts over the past two decades.
Purpose of the Study:
- To provide an overview of epidemiological and implementation research activities in onchocerciasis control in Africa.
- To assess the impact of this research on control program effectiveness and operational planning.
Main Methods:
- Development and application of epidemiological modeling for program evaluation.
- Disease pattern and burden studies across diverse bioclimatic zones.
- Community trials of ivermectin for safety, efficacy, and transmission impact.
- Development of rapid assessment tools and community-directed treatment strategies.
Main Results:
- Epidemiological modeling enhanced program evaluation and operational planning.
- Understanding disease burden guided control operations.
- Ivermectin demonstrated safety and impact on transmission, supporting large-scale use.
- Community-directed approaches ensured sustained drug delivery.
Conclusions:
- A strong research-control collaboration has been vital for onchocerciasis control success in Africa.
- Lessons learned emphasize the importance of adaptive strategies and community engagement for sustainable disease elimination.