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Aminopyridine-benzoxanthene enantioselective receptor for sulfonylamino acids
Ana I Oliva1, Luis Simón, Francisco M Muñiz
1Department of Organic Chemistry, University of Salamanca, Plaza de los Caídos, 1-5, Salamanca 37008, Spain.
Abstract:
Combination of a cis-tetrahydrobenzoxanthene skeleton with a benzoxazole and an amidopyridine provides an enantioselective receptor for sulfonylamino acids with chiral recognitions of up to 18. The structure of the complex between receptor 1 and the leucine triflate is known by X-ray analysis. The receptor racemic mixture can be suitably resolved through crystalization in the presence of leucine triflate as guest. Receptor 1 can be used for the enantioselective extraction of sulfonylamino acids from aqueous solutions of their salts.
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