Related Experiment Video
Updated: Aug 25, 2026

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
Published on: December 2, 2014
Evaluation of aortic stiffness in tobacco-smoking adolescents
Ertürk Levent1, Arif Ruhi Ozyürek, Zülal Ulger
1Faculty of Medicine, Department of Pediatric Cardiology, Ege University, Bornova, Izmir, Turkey. erturk@med.ege.edu.tr
Purpose:
To measure the aortic stiffness in tobacco-smoking adolescents and to investigate its relationship to tobacco smoke.
Methods:
Aortic strain (S), pressure strain elastic modulus (E(p)), and normalized E(p) (E(p)*) in tobacco-smoking adolescents and the healthy control group were measured by a sphygmomanometer with cuff and transthoracic echocardiography. The study group consisted of 30 healthy cases (M/F: 27/3) as a control group and 30 tobacco-smoking volunteer adolescents (M/F: 28/2). Unpaired Student's t-test was used for comparison of these groups.
Results:
The mean ages were 16.1 +/- 1.8 years and 16.2 +/- 1.4 years, respectively. The number of cigarettes smoked per day was 31 +/- 7.1 and the duration of smoking was 3.4 +/- 1.1 years. S, E(p) and E(p)* measurements of tobacco smokers were different than the control groups' and this difference was statistically significant. S values were significantly higher in nonsmokers than in smokers; whereas E(p) and E(p)* values were significantly higher in smoker group.
Conclusions:
This study demonstrated that measurement of aortic stiffness with S, E(p), and E(p)* can be used as an early indicator of atherosclerosis in tobacco-smoking adolescents.
Related Concept Videos
Assessment of blood pressure in brachial artery(two-step method)
Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
