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Related Experiment Videos

Total and segmental liver volume variations: implications for liver surgery.

Eddie K Abdalla1, Alban Denys, Patrick Chevalier

  • 1Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

Surgery
|March 26, 2004
PubMed
Summary

Liver remnant and graft volumes impact surgical outcomes. This study quantizes hepatic segment contributions to total liver volume (TLV), revealing significant patient-to-patient variations crucial for surgical planning.

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Area of Science:

  • Hepatobiliary surgery
  • Surgical anatomy
  • Medical imaging

Background:

  • Liver remnant and graft volumes are critical for surgical outcomes in liver resection and transplantation.
  • Accurate quantification of hepatic segment contributions to total liver volume (TLV) is not well-established.

Purpose of the Study:

  • To determine the relative contributions of individual hepatic segments to the total liver volume (TLV).
  • To establish baseline volumetric data for hepatic segments in a healthy adult population.

Main Methods:

  • Computed tomography (CT) was used to measure TLV and hepatic segment volumes in 102 patients without liver disease.
  • Patients were selected based on CT scans performed for non-liver-related conditions.

Main Results:

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  • Total liver volume (TLV) ranged from 911 to 2729 cm(3).
  • The right liver averaged two-thirds of TLV, while the left liver averaged one-third.
  • Significant interpatient variability was observed in the proportion of TLV contributed by the right liver (49-82%) and left liver (17-49%).

Conclusions:

  • Clinically significant interpatient variations in hepatic volumes necessitate careful pre-operative assessment.
  • Routine measurement of future liver remnant is recommended before extended right hepatectomy.
  • Pre-operative volumetric assessment is advised for selected right hepatectomy cases anticipating a small left liver remnant.