Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebral infarction in eclampsia.

Gerda G Zeeman1, James L Fleckenstein, Diane M Twickler

  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Tex, USA. g.g.zeeman@isala.nl

American Journal of Obstetrics and Gynecology
|March 26, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prior Stillbirth is Associated with Increased Risk of Subsequent Stillbirth.

American journal of obstetrics and gynecology·2026
Same author

Eclampsia despite magnesium sulfate prophylaxis.

American journal of obstetrics & gynecology MFM·2026
Same author

Long-term risk of hypothyroidism after thyroid abnormalities identified in pregnancy.

American journal of obstetrics and gynecology·2026
Same author

First-trimester risk stratification algorithm for placenta accreta spectrum.

American journal of obstetrics & gynecology MFM·2026
Same author

Magnesium sulfate for the prevention of seizures in preeclampsia: origin, experimental basis, clinical studies, and the evolution in obstetrical practice.

American journal of obstetrics and gynecology·2025
Same author

Ensemble of fine-tuned machine learning models for hysterectomy prediction in pregnant women using magnetic resonance images.

Journal of medical imaging (Bellingham, Wash.)·2025
Same journal

Likelihood ratios enhance clinical interpretation of metagenomic prediction of early-onset neonatal sepsis in preterm premature rupture of membranes (Letter-to-the-Editor).

American journal of obstetrics and gynecology·2026
Same journal

Taking risk stratification in preterm premature rupture of membranes to the bedside (Reply to Letter-to-the-Editor).

American journal of obstetrics and gynecology·2026
Same journal

Gestational Age at Full-Term Delivery and Long-Term Offspring Morbidity in Low-Risk Pregnancies: A Population-Based Cohort Study.

American journal of obstetrics and gynecology·2026
Same journal

Trajectories of childbirth-related posttraumatic stress symptoms after a vaginal delivery: a multicenter prospective study.

American journal of obstetrics and gynecology·2026
Same journal

Early life adversity and polycystic ovary syndrome among North American pregnancy planners.

American journal of obstetrics and gynecology·2026
Same journal

Survival assessment of adjuvant chemotherapy for cytology-negative, non-myoinvasive stage IC clear cell endometrial cancer.

American journal of obstetrics and gynecology·2026
See all related articles

Neuroimaging reveals that cerebral edema in eclampsia, often reversible vasogenic edema, can progress to cytotoxic edema and infarction in some women. Diffusion-weighted MRI helps characterize these brain lesions.

Area of Science:

  • Neurology
  • Radiology
  • Obstetrics

Background:

  • Eclampsia is a severe complication of pregnancy characterized by seizures.
  • Cerebral edema is a known complication of eclampsia, but its neuroimaging characteristics are not fully understood.

Purpose of the Study:

  • To characterize the neuroimaging findings of cerebral edema in eclamptic seizures using diffusion-weighted magnetic resonance imaging (MRI).

Main Methods:

  • Diffusion-weighted MRI and apparent diffusion coefficient mapping were used to evaluate 27 nulliparous women with eclampsia.
  • Follow-up neuroimaging was performed 6 weeks postpartum for women with findings suggestive of cytotoxic edema.

Main Results:

  • Ninety-three percent of women exhibited reversible vasogenic edema.

Related Experiment Videos

  • Six women also had cytotoxic edema, indicative of cerebral infarction.
  • Five of these six women showed persistent infarction findings postpartum, yet without clinical neurological deficits.

    • Conclusions:

    • The spectrum of cerebral lesions in eclampsia varies.
    • Reversible vasogenic edema can progress to cytotoxic edema and infarction in up to 25% of women.
    • Diffusion-weighted MRI is valuable for assessing these brain lesions.