Related Experiment Videos
The association of parity with mortality outcomes among triplets
Hamisu M Salihu1, Muktar H Aliyu, Dwight J Rouse
1Department of Maternal and Child Health, University of Alabama at Birmingham, Birmingham, Alabama, USA. hsalihu@uab.edu
Objective:
The purpose of this study was to evaluate the association of parity with stillbirth and neonatal and infant death among triplets.
Study Design:
This was a retrospective cohort study of 15,930 triplets who were delivered in the United States between 1995 and 1997. Infants of nulliparous mothers were compared with infants of multiparous mothers. Adjusted relative risks for death by parity were computed with the use of the generalized estimating equations framework.
Results:
The likelihood for stillbirth (odds ratio, 3.40; 95% CI, 2.20-5.26) was significantly greater among nulliparous mothers. Neonatal (odds ratio, 1.17; 95% CI, 0.95-1.43) and infant mortality rates (odds ratio, 1.10; 95% CI, 0.92-1.32) were comparable, however. With an increase in parity, there was a consistent declining trend in the risk for stillbirth (P<.0001).
Conclusion:
Nulliparity more than triples the risk for intrauterine fetal death among triplets. This parity-related disparity underscores the need for care providers to be particularly concerned about triplet gestations among nulliparous mothers.
Related Concept Videos
Regression Toward the Mean
Probability Laws
Truncation in Survival Analysis
Left truncation occurs when individuals who experienced the event of interest before a certain time are not included in the study. This is often due to a "delayed entry" into the study where only those who survive until a certain entry point are observed.
Hazard Ratio
For example, in a clinical trial evaluating a...
Relative Risk
Odds Ratio