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Can measles be eradicated globally?
1Sabin Vaccine Institute, Washington, DC, USA. ciro.dequadros@sabin.org
Abstract:
Measles is one of the most infectious diseases. Before measles vaccine was introduced, nearly everyone contracted the disease at some point in childhood. By the late 1980s, most countries had incorporated measles vaccine into their routine immunization programmes. Globally, about 800 000 children nevertheless still die from measles annually, half of them in Africa. Eradicating measles would therefore play an important role in improving children's survival. The 24th Pan American Sanitary Conference in 1994 established a goal of eradicating measles from the Americas. Progress to date has been remarkable and the disease is no longer endemic in the Americas, with most countries having documented interruption of transmission. As of November 2003, 12 months had elapsed since the last indigenous case was detected in Venezuela. This experience shows that measles transmission can be interrupted, and that this can be sustained over a long period of time. Global eradication is feasible if an appropriate strategy is implemented. Even under a new paradigm in which immunization is not discontinued after measles is eradicated, eradication will be a good investment to avoid expensive epidemics and save the lives of almost one million children annually. A world free of measles by 2015 is not a dream.
Insights
Measles eradication is achievable, as demonstrated by its elimination in the Americas. Continued global immunization efforts can prevent millions of childhood deaths annually.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Measles is a highly contagious childhood illness, historically affecting nearly all children before widespread vaccination.
- Despite the introduction of the measles vaccine by the late 1980s, approximately 800,000 children globally, primarily in Africa, still succumb to measles annually.
- Measles eradication is crucial for improving global child survival rates.
Purpose of the Study:
- To assess the feasibility and impact of measles eradication strategies.
- To highlight the success of measles elimination efforts in the Americas as a model for global eradication.
Main Methods:
- Review of global measles vaccination programs and their impact.
- Analysis of the Pan American Sanitary Conference's 1994 goal for measles eradication in the Americas.
- Examination of transmission interruption data and sustained disease control.
Main Results:
- Measles is no longer endemic in the Americas, with documented interruption of transmission in most countries.
- Venezuela reported its last indigenous measles case over 12 months prior to November 2003, demonstrating sustained control.
- The experience in the Americas proves that measles transmission can be interrupted and maintained at zero levels.
Conclusions:
- Global measles eradication is feasible with the implementation of a suitable strategy.
- Sustained immunization programs, even post-eradication, represent a sound investment to prevent costly epidemics and save nearly one million lives annually.
- Achieving a measles-free world by 2015 is a realistic and attainable objective.
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