Related Experiment Video
Updated: Aug 25, 2026

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
Published on: January 12, 2020
[oct-genes and oct-proteins]
1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Abstract:
The review considers the functions and properties of Oct proteins, which belong to the POU family of transcription factors, and the roles of the POU and other domains in DNA recognition and interaction with other proteins of the transcription initiation complex. The structure and expression regulation of the oct genes are described with special emphasis on alternative transcription initiation from different promoters and alternative splicing, which result in several protein subforms.
More Related Videos
Related Concept Videos
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein.
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein.
Constitutive and Regulated Gene Expression
Organization of Genes

