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Aspirin therapy and bleeding during proximal femoral fracture surgery

Yoram Anekstein1, Eran Tamir, Nahum Halperin

  • 1Department of Orthopaedic Surgery, Assaf-Harofe Medical Center, Zerifin, Israel. nuritan@internet-zahav.net

Clinical Orthopaedics and Related Research
|March 27, 2004
PubMed

Insights

Daily low-dose aspirin therapy did not significantly increase major bleeding during proximal femoral fracture surgery. Patients taking aspirin required slightly more blood transfusions, but overall, surgery remained safe for this group.

Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Pharmacology

Background:

  • Perioperative bleeding is a concern in orthopedic surgery.
  • Aspirin is commonly used for cardiovascular prevention and may affect surgical bleeding.

Purpose of the Study:

  • To evaluate the impact of daily low-dose aspirin on perioperative bleeding in patients undergoing surgery for proximal femoral fractures.

Main Methods:

  • Prospective case-control study involving 104 patients over 14 months.
  • 39 patients were on aspirin therapy prior to injury.
  • Bleeding assessed by blood units transfused, hemoglobin change, complications, and drain volume.

Main Results:

  • Aspirin group received 0.5 units more blood transfusions postoperatively (statistically significant).
  • No significant differences observed in other bleeding parameters (hemoglobin change, drain volume).
  • No major bleeding complications were reported in either group.

Conclusions:

  • Surgery for proximal femoral fractures is safe for patients taking daily low-dose aspirin.
  • While a slight increase in transfusion needs may occur, major bleeding risks are not elevated.

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