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Intercalating nucleic acids: the influence of linker length and intercalator type on their duplex stabilities
Ulf B Christensen1, Michael Wamberg, Farag A G El-Essawy
1Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense, Denmark.
Nucleosides, Nucleotides & Nucleic Acids
|March 27, 2004
Abstract:
Six new examples of intercalating nucleic acids were synthesized in order to evaluate the dependence of the length of the linker between oligo and intercalator on the thermal stability of their corresponding duplexes and triplexes.