New peptaibols from Mycogone cervina
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Published on: August 6, 2019
Corinne Wilhelm1, Heidrun Anke, Yonny Flores
1Institute for Biotechnology and Drug Research, Erwin-Schroedinger-Strasse 56, D-67663 Kaiserslautern, Germany.
Abstract:
From cultures of Mycogone cervina, a mycophilic fungus growing on the fruit bodies of ascomycete Paxina acetabulum, two new peptaibols (cervinin, N-Ac-Leu-Aib-Pro-Aib-Leu-Aib-Pro-Ala-Aib-Pro-Val-red-Leu (1) and the red-Leu O-acetylated derivative 2) were isolated. The structures of 1 and 2 were elucidated by spectroscopic techniques. They exhibited weak antibacterial as well as cytotoxic activities. They are the first secondary metabolites described from M. cervina.
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