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Updated: Aug 25, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
Published on: January 26, 2024
The DISOPRED server for the prediction of protein disorder
Jonathan J Ward1, Liam J McGuffin, Kevin Bryson
1Bioinformatics Group, Department of Computer Science, University College London, Gower Street, London, WC1E 6BT, UK.
Unlabelled:
Dynamically disordered regions appear to be relatively abundant in eukaryotic proteomes. The DISOPRED server allows users to submit a protein sequence, and returns a probability estimate of each residue in the sequence being disordered. The results are sent in both plain text and graphical formats, and the server can also supply predictions of secondary structure to provide further structural information.
Availability:
The server can be accessed by non-commercial users at http://bioinf.cs.ucl.ac.uk/disopred/
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