Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diiminoisoindoline: tautomerism, conformations, and polymorphism.

Zhi-Qin Zhang1, Jeffrey M Njus, Daniel J Sandman

  • 1Center for Advanced Materials, Department of Chemistry, University of Massachusetts Lowell, Lowell, Massachusetts 01854-5046, USA.

Chemical Communications (Cambridge, England)
|March 27, 2004
PubMed
Summary

Two polymorphs of diiminoisoindoline exist in the amino tautomeric form. One is a conformational isomorph with syn- and anti-isomers, while the other is a polymorph with only the syn-isomer.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Abnormal elevated PANX1 expression hampers endometrial decidualization by upregulating extracellular ATP concentration in patients with recurrent implantation failure.

Scientific reports·2026
Same author

CPOP1 is a key enzyme required for nodule microenvironment control and successful symbiotic nitrogen fixation in Lotus japonicus.

Journal of integrative plant biology·2025
Same author

Mutations of short tandem repeats explain abundant trait heritability in Arabidopsis.

Genome biology·2025
Same author

Polymorph Screening and Investigation of Charge Transport of ditBuC6-BTBT.

Crystal growth & design·2025
Same author

Crystal Engineering in Oligorylenes: The Quest for Optimized Crystal Packing and Enhanced Charge Transport.

Crystal growth & design·2025
Same author

Pterostilbene Exhibited the Anticancer Effect Against 1, 2-Dimethylhydrazine (DMH)-Induced Colorectal Cancer via Alteration of Oxidative Stress, Inflammation and Gut Microbiota.

Journal of biochemical and molecular toxicology·2025

Area of Science:

  • Solid-state chemistry
  • Crystallography
  • Organic chemistry

Background:

  • Diiminoisoindoline is an industrially significant compound.
  • Polymorphism impacts material properties and industrial applications.
  • Understanding tautomeric forms is crucial for chemical characterization.

Purpose of the Study:

  • To investigate the structural characteristics of diiminoisoindoline polymorphs.
  • To elucidate the tautomeric forms and isomeric composition of diiminoisoindoline.
  • To differentiate between conformational isomorphism and polymorphism in diiminoisoindoline.

Main Methods:

  • Single-crystal X-ray diffraction analysis.
  • Spectroscopic techniques for tautomer identification.
  • Crystallographic data analysis to determine isomeric ratios.

Related Experiment Videos

Main Results:

  • Identified two distinct polymorphs of diiminoisoindoline.
  • Characterized one polymorph as a conformational isomorph containing a 1:1 mixture of syn- and anti-isomers.
  • Determined the second polymorph to be a conformational polymorph exclusively containing the syn-isomer.
  • Confirmed the amino tautomeric form for both polymorphs.

Conclusions:

  • The study reveals the complex solid-state behavior of diiminoisoindoline.
  • Distinct conformational and isomeric arrangements define the observed polymorphs.
  • Understanding these structural variations is key for controlling diiminoisoindoline's industrial utility.