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[Current concepts and recent developments of laser ablation in tumor therapy]
C Stroszczynski1, G Gaffke, M Gnauck
1Klinik für Strahlenheilkunde der Charité, Campus-Virchow-Klinikum und Campus Buch-Medizinische Fakultät der Humboldt-Universität zu Berlin. stros@charite.de
Purpose:
The purpose of this paper is to present technical innovations and clinical results of percutaneous interventional laser ablation of tumors using new techniques. METHODS; Laser ablation was performed in 182 patients (liver tumors: 131, non hepatic tumors-bone, lung, others: 51) after interdisciplinary consensus was obtained. The procedure was done using a combination of imaging modalities (CT/MRI, CT/US) or only closed high field MRI (1.5 T). All patients received an MRI-scan immediately after laser ablation.
Results:
In 90.9% of the patients with liver tumors, a complete ablation was achieved. Major events occurred in 5.4%. The technical success rate of laser ablation in non-hepatic tumors was high, clinical results differed depending on the treated organ.
Conclusions:
The treatment of tumors of the liver and other organs up to 5 cm by laser ablation was a safe procedure with a low rate of complications and side effects. Image guidance by MRI is advantageous for precise tumor visualization in all dimensions, therapy monitoring, and control of laser ablation results.