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Protective effect of breastfeeding against urinary tract infection
1Department of Paediatrics, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Göteborg, Sweden. staffan.marild@pediat.gu.se
Insights
Exclusive breastfeeding significantly lowers the risk of febrile urinary tract infections (UTIs) in children. This protective effect, linked to breast milk
Area of Science:
- Pediatrics
- Infectious Diseases
- Immunology
Background:
- Urinary tract infections (UTIs) are common in children.
- The role of breastfeeding in preventing infections is an area of ongoing research.
Purpose of the Study:
- To evaluate the protective effect of exclusive breastfeeding against first-time febrile urinary tract infections (UTIs) in young children.
Main Methods:
- A prospective case-control study was conducted with 200 children diagnosed with their first febrile UTI and 336 matched controls.
- Data on the duration of exclusive breastfeeding was collected using a standardized method.
Main Results:
- Ongoing exclusive breastfeeding was associated with a significantly reduced risk of febrile UTI.
- A longer duration of breastfeeding showed a continued protective effect even after weaning, suggesting a long-term mechanism.
- The protective effect was most pronounced in early infancy, diminishing by 7 months of age.
Conclusions:
- Breastfeeding demonstrates a significant protective role against urinary tract infections in children.
- These findings support the concept of breast milk as a natural defense mechanism against UTIs.
Aim:
To assess the possible protective effect of exclusive breastfeeding against first-time febrile urinary tract infection (UTI) in children.
Methods:
Two children's hospitals and local child health centres in the Göteborg area, Sweden, participated in a prospective case-control study. In total, 200 consecutive cases (89M, 111F), aged 0-6y, presenting with first-time febrile UTI were enrolled. The mean +/- SD age was 0.98 +/- 1.15 y. As control subjects, 336 children (147M, 189F) were recruited from the child health centre of the case, matched for age and gender and included consecutively for each case during the first days after diagnosis. The duration of exclusive breastfeeding was obtained from the case and controls by a standardized procedure.
Results:
Ongoing exclusive breastfeeding gave a significantly lower risk of infection. A longer duration of breastfeeding gave a lower risk of infection after weaning, indicating a long-term mechanism. The protective role of breastfeeding was strongest directly after birth, then decreased until 7 mo of age, after which age no effect was demonstrated.
Conclusion:
A protective role of breastfeeding against UTI was demonstrated. The study provides statistical support to the view that breast milk is a part of the natural defence against UTI.
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