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The MHC: relationship between linkage and function
1Human Immunogenetics Laboratory, Imperial Cancer Research Fund, Hoborn, London, UK.
Current Opinion in Genetics & Development
|June 1, 1992
Abstract:
It is intriguing that several genes with associated functions, including all of class I and class II genes, as well as some genes affecting antigen presentation of both class I and class II pathways, are linked in the MHC. Recent observations have led to speculation that there may be a functional explanation for keeping these related genes together.