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Kikuchi-Fujimoto disease with lateral neck localisation: a case report
1Otorhinolaryngology Unit, University Hospital, Cagliari, Italy. biggioandrea@tiscalinet.it
Summary
Kikuchi-Fujimoto disease, a rare cause of neck lymphadenopathy, requires histological confirmation for accurate diagnosis. Early consideration by ENT specialists is crucial for prompt patient management.
Area of Science:
- Pathology
- Immunology
Background:
- Kikuchi-Fujimoto disease (KFD) is a rare, benign, and self-limiting condition characterized by necrotizing lymphadenitis.
- Diagnosis can be challenging due to non-specific clinical and radiological presentations.
Observation:
- A case of KFD in a 22-year-old female presented with rapidly progressing lateral neck lymphadenopathy.
- Initial clinico-radiological findings suggested a lymphoproliferative disorder, necessitating further investigation.
Findings:
- Histological examination of a lymph node biopsy revealed a characteristic pattern of necrotizing lymphadenitis, confirming the diagnosis of KFD.
- The study highlights the diagnostic difficulties associated with KFD, including its variable clinical course and non-specific imaging results.
Implications:
- Histological examination is paramount for the definitive diagnosis of KFD.
- ENT specialists should consider KFD in young patients with rapidly evolving lateral neck lymphadenopathy, even in the absence of other clear causes.