Related Experiment Videos
Feasibility of adenovirus-mediated gene transfer in vivo
L D Stratford-Perricaudet1, P Briand, M Perricaudet
1UA 1301 of CNRS, Institut Gustave Roussy, Villejuif, France.
Bone Marrow Transplantation
|January 1, 1992
Abstract:
We have evaluated the use of Adenovirus as a new vector for gene transfer in vivo. The capacity of this virus to express a foreign gene even in the absence of viral and cellular replication makes it attractive to deliver a gene to quiescent cells. We show here that organs like lung, liver and muscles are relevant to this strategy.