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Generation of highly stable IL-18 based on a ligand-receptor complex structure

Yutaka Yamamoto1, Zenichiro Kato, Eiji Matsukuma

  • 1Department of Pediatrics, Gifu University School of Medicine, Tsukasa 40, Gifu 500-8705, Japan.

Summary

Researchers created a more stable human interleukin-18 (hIL-18) protein by altering its structure. This enhanced stability is crucial for reliable therapeutic applications, particularly in cancer treatment.

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