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Related Experiment Videos

Inducible syncope in anorexia nervosa: two case reports.

Katherine P Buchowski1, Jennifer Pardo, Richard Ringel

  • 1Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. kpiyaka@jhmi.edu

The International Journal of Eating Disorders
|March 30, 2004
PubMed
Summary

Anorexia nervosa patients can self-induce syncope through isometric exercise, potentially due to heightened vagal tone. This dangerous behavior requires medical attention and awareness during treatment.

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Area of Science:

  • Cardiology
  • Psychiatry
  • Pediatrics

Background:

  • Syncope is a recognized, potentially dangerous symptom in individuals with anorexia nervosa.
  • It is typically attributed to physiological factors such as bradycardia, dehydration, or hypoglycemia.

Observation:

  • This case study details two adolescents (one male, one female) experiencing recurrent, self-induced syncope.
  • The syncope episodes were specifically associated with performing isometric exercise.

Findings:

  • Holter monitoring in one patient revealed that isometric exercise induced progressive bradycardia.
  • This was followed by asystolic pauses, correlating with the onset of presyncopal symptoms.

Implications:

  • The study hypothesizes that increased vagal tone and baroreceptor sensitivity trigger inducible syncope in these patients.

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  • Physicians must recognize that anorexia nervosa patients may induce syncope via isometric exercise, necessitating intervention.
  • This potentially harmful behavior requires careful assessment and management within the treatment plan.