[Selective serotonin reuptake inhibitors (SSRIs) antidepressants use in hot flashes in oncology]

Menopausal women or patients treated by chemotherapy or hormonotherapy for breast cancer have often disabled hot flashes. Men with prostate cancer confronted to castration can also suffer from the same problem. In both situations, many arguments go against implementation of estrogenic treatment. Albeit, many complementary therapeutics exist, they are often unsatisfying.

Since some years, anecdotal case reports and controlled studies have reported interest of selective serotonin reuptake inhibitors (SSRIs) antidepressants in this indication. These treatments often appear efficient and well tolerated.

Through a review of literature and clinical vignette, we will specify physiopathology and prescription modalities in this new type of indication.