Related Experiment Video
Updated: Aug 25, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
[A case of association of atypical localisations of Streptococcus pneumoniae]
H Quintard1, F Pène, C Ginsburg
1Service de réanimation médicale, hôpital Cochin, 27, rue du faubourg Saint-Jacques, 75679 Paris cedex 14, France.
Abstract:
Streptococcus pneumoniae can be responsible for spinal, joints, pulmonary or infrequently cutaneous septic localisations. The association between different septic localisation is extremely rare with this microorganism. We describe the first case of concomitant spinal, joints and cutaneous septic localisations in a critically ill patient with S. pneumoniae septicaemia. This observation illustrates that heterogeneity of clinical features depends on the pathogen characteristic and its interaction with the host.
Insights
Streptococcus pneumoniae rarely causes multiple infections simultaneously. This case report details the first instance of concurrent spinal, joint, and skin infections in a critically ill patient with pneumococcal sepsis.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Streptococcus pneumoniae is a common pathogen causing various infections, including pulmonary, joint, and spinal disease.
- Disseminated S. pneumoniae infections with multiple distinct septic localizations are exceptionally rare.
- Understanding pathogen-host interactions is crucial for predicting infection patterns.
Observation:
- This report describes a unique case of a critically ill patient with S. pneumoniae sepsis.
- The patient presented with simultaneous septic involvement of the spine, joints, and skin.
- This represents the first documented case of concomitant spinal, joint, and cutaneous S. pneumoniae infections.
Findings:
- The study highlights an extremely rare presentation of S. pneumoniae infection.
- Concurrent septic localizations in the spine, joints, and skin were observed in a single patient.
- The findings underscore the pathogen's potential for diverse clinical manifestations.
Implications:
- This case emphasizes the importance of considering unusual presentations of S. pneumoniae infections.
- It suggests that pathogen characteristics and host factors significantly influence the heterogeneity of clinical features.
- Further research into S. pneumoniae virulence and host immune responses may elucidate such rare presentations.
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Streptococcal Pharyngitis
Pneumonia III: Complications and Assessment
Bacterial Meningitis I: Introduction

