Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sustainable Development01:43

Sustainable Development

15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
Language Development01:22

Language Development

941
Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
941
Development of the Lymphatic System01:15

Development of the Lymphatic System

2.2K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.2K
Development of Immunocompetence01:22

Development of Immunocompetence

1000
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1000
Development of the Heart01:27

Development of the Heart

2.7K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
2.7K
Fruit Development, Structure, and Function01:58

Fruit Development, Structure, and Function

25.5K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Awake Nebulized Indocyanine Green (ICG) for Tracheobronchial Fluorescence: A Safety and Feasibility Study in Minimally Invasive Esophagectomy.

Indian journal of surgical oncology·2026
Same author

Musculoskeletal Symptoms and Post-COVID Functional Status among COVID-19 Survivors: A Single-Center Prospective Observational Study.

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine·2026
Same author

Upfront surgery versus induction chemotherapy followed by surgery in oral cavity squamous cell cancers with advanced nodal disease (SurVIC Trial): a phase 3 multicentre randomised controlled trial.

BMJ open·2025
Same author

Vitamin D in Disease Prevention and Cure-Part I: An Update on Molecular Mechanism and Significance on Human Health.

Indian journal of clinical biochemistry : IJCB·2025
Same author

EPR25-132: Hospital-Based Cancer Registry (HBCR) Data Analysis for Women at a Tertiary Care Center in North India.

Journal of the National Comprehensive Cancer Network : JNCCN·2025
Same author

Transporter Associated with Antigen Processing Proteins (TAP-1 and TAP-2) Gene Expression of MHC-I Downregulated in Oral Squamous Carcinoma.

Endocrine, metabolic & immune disorders drug targets·2025

Related Experiment Video

Updated: Feb 14, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

860

Penile carcinoma: a challenge for the developing world.

Sanjeev Misra1, Arun Chaturvedi, Naresh C Misra

  • 1Department of Surgical Oncology, King George's Medical College, Lucknow, India.

The Lancet. Oncology
|March 31, 2004
PubMed
Summary

Penile carcinoma is a significant health issue in developing nations, with childhood circumcision offering the best prevention. Early detection and organ-preserving treatments are key for managing this rare cancer.

More Related Videos

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
07:28

Microscopic Replantation of Penile Glans Amputation Due to Circumcision

Published on: June 3, 2022

25.3K
Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo
10:18

Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo

Published on: September 11, 2018

6.3K

Related Experiment Videos

Last Updated: Feb 14, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

860
Microscopic Replantation of Penile Glans Amputation Due to Circumcision
07:28

Microscopic Replantation of Penile Glans Amputation Due to Circumcision

Published on: June 3, 2022

25.3K
Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo
10:18

Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo

Published on: September 11, 2018

6.3K

Area of Science:

  • Oncology
  • Urology
  • Public Health

Background:

  • Penile carcinoma, though rare in developed countries, poses a significant health challenge in developing regions.
  • Childhood circumcision is identified as a primary preventive measure against penile cancer.
  • Key risk factors include poor penile hygiene and phimosis, contributing to cancer development.

Purpose of the Study:

  • To review the epidemiology, risk factors, and management strategies for penile carcinoma.
  • To highlight treatment modalities for early and advanced stages of the disease.
  • To emphasize the need for further research on chemotherapy's role in metastatic penile cancer.

Main Methods:

  • Literature review of penile carcinoma epidemiology and treatment.
  • Analysis of risk factors such as hygiene and phimosis.
  • Overview of surgical (resection, penectomy, lymphadenectomy) and non-surgical (Mohs surgery, laser, radiation) interventions.

Main Results:

  • Early-stage penile cancer is treatable with conventional resection or organ-preserving techniques.
  • Advanced disease necessitates partial or total penectomy.
  • Lymph-node dissection is crucial for managing inguinal metastatic disease.

Conclusions:

  • Childhood circumcision provides substantial protection against penile carcinoma.
  • Prompt diagnosis and appropriate surgical or organ-preserving interventions are vital for effective management.
  • Prospective clinical trials are needed to determine the efficacy of chemotherapy in metastatic penile cancer, particularly in developing countries.