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Updated: Aug 25, 2026

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Published on: November 21, 2013
Is lateral bias anomalous in early-onset schizophrenia? Selected comparisons with normal populations
Simon L Collinson1, Tania Jane Phillips, Anthony C D James
1Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK. scollinson@mhri.edu.au
Abstract:
The aim of this study was to investigate lateral bias in patients with early-onset schizophrenia. Hand, eye, and foot preferences and relative hand skill were examined in early-onset patients (n=44) and matched controls (n=39), and were compared with population estimates. Patients demonstrated a significant excess in mixed handedness (20.5% vs. 8.5%) relative to population estimates and reduced relative hand skill on a pegboard task compared with controls. Left eye preference was significantly less common in schizophrenic patients relative to population estimates. Crossed eye-hand and eye-foot preferences were not significantly increased in the patient group as a whole but were present, respectively, in four of nine and five of nine mixed-handed patients but in none of five mixed-handed controls. These findings are consistent with the view that lateralisation is anomalous in schizophrenia early in the course of illness.
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